new complications for COVID vaccines in the US

(COVID Photo by Martin Sanchez on Unsplash)

Last week, after reading a newsletter from Your Local Epidemiologist founded by Dr. Katelyn Jetelina, I got a COVID vaccination. I will be going to my annual poetry residency with the Boiler House Poets Collective at The Studios at MASS MoCA in early October and wanted my immunity to be as strong as possible while I’m there.

The newsletter had warned that there might be label changes coming from the US Food and Drug Administration that would impact the availability of COVID vaccines and that it might be advisable to get the vaccine soon, especially for people younger than 65.

I’m glad I took action.

Yesterday, the Food and Drug Administration changed the guidelines, making it more difficult for people under 65 to qualify for COVID vaccines without consulting their doctor. In response, CVS and Walgreens, whose pharmacies are a major source for vaccinations to the public, suspended giving any COVID vaccines to anyone in sixteen states, including mine, unless you have a prescription from a health provider. Part of the confusion is that the Centers for Disease Control and Prevention has yet to issue its guidance and just suffered the loss of its top leadership through firing and resignations, grounded in the fact that they were being pressured to put forward recommendations not backed by scientific research.

That’s what happens when you have a Health and Human Services Secretary like Robert Kennedy, Jr., who does not have a background in medicine and disrespects rigorous scientific inquiry.

The fact is that COVID-19 vaccines have been rigorously tested and are safe and effective, cutting down on infection rates and keeping most people from becoming seriously ill and needing hospitalization. Serious side effects are very rare, so the benefits of receiving the vaccine outweigh the risks.

Tragically, vaccines have been politicized in the US, which has cost lives. The death rate from COVID-19 for Republicans is higher than for the population as a whole because of this.

I urge everyone with questions to talk to a trusted medical professional about the research and science behind vaccines. Don’t fall for the misinformation coming from Kennedy and the people he has put in place at the CDC and FDA who disregard valid scientific findings.

You can also look for recommendations from medical associations, such as the American Academy of Pediatrics.

Don’t let misinformation keep you from taking the best care possible of your and your family’s health.

5 years of COVID-19

(COVID Photo by Martin Sanchez on Unsplash)

The COVID-19 pandemic shutdowns began in the United States five years ago this month. I’ve written a lot of posts about it over those years and I’m proud to say that they have been added to the archives of the Newark Valley (NY) Historical Society to be preserved for future research.

To date, there has only been one case in our household, when B contracted it at a work event in November, 2023. Fortunately, T and I did not get sick.

All three of us participated in Phase III clinical trials for the Pfizer/BioNTech vaccine and have kept up to date on recommended doses as the virus has mutated into new variants over these past five years. We’ve also taken other precautions, such as masking and avoiding crowds when virus levels are high. Admittedly, it’s been harder and harder to get information about virus levels in our area as the public health emergency lapsed and reporting became optional.

I do still get some public health and long COVID newsletters that give some information. I found out today, for example, that there is a new variant, BA.3.2, in South Africa that has 50 new spike mutations. It could stay localized and fizzle out; if it out-competes other strains and spreads, it could create a wave similar to Omicron.

As far as the United States goes, I’m concerned that the vaccination rates are likely to fall even further with a vaccine skeptic now in charge of the Department of Health and Human Services. The United States has already suffered over 1.2 million deaths from COVID with millions more dealing with long-lasting health repercussions. Vaccines can help people avert more severe symptoms and decrease the chances of being infected but work best if a large proportion of the population are vaccinated. This also helps protect people who have more fragile immune systems, such as the very young, elders, and people with compromised immune systems.

I believe that information is power, but it needs to be factual information, not wishful thinking or political posturing. We can’t pretend that the virus doesn’t still kill or sicken people and that the United States is not continuing to lose hundreds of people each week due to COVID-19.

To deny the existence of COVID and/or its impact on our lives dishonors those we have lost, those who have been sickened by the virus, their loved ones, and their communities.

Take care of each other and do what you can to keep us all as healthy as possible.

Summer ’24 COVID wave

(COVID Photo by Martin Sanchez on Unsplash)

It’s become more difficult to keep track of COVID-19 cases here in the United States, as less data is being collected and shared with the public.

We do know that this summer’s wave has been substantial, mostly due to the Omicron subvariants known as FLiRT. While death rates have been lower than in previous waves, they have still been ranging in the 400s-700s per week this summer, which is upsetting. These figures may also be lower than the actual count because reporting is less robust than it was under the public health emergency protocols.

Last week, the US Food and Drug Administration approved the Pfizer and Moderna vaccines based on the KP.2 variant, one of the FLiRT family. Doses are already available from some pharmacies and are recommended for everyone ages 6 months and older. While some people will choose to wait until later in the fall to have the strongest protection possible going into the expected winter wave, I will be getting mine in mid-September so that my immunity will be strong when I go to North Adams for the annual Boiler House Poets Collective residency at MASS MoCA (Massachusetts Museum of Contemporary Arts). It looks as though the vaccine will be a good match for the strains that will likely be dominant in the coming months.

The FDA is also expected to approve the Novavax vaccine in the coming weeks. It is a more traditional protein-based vaccine rather than an mRNA one. Some people prefer it because it can cause fewer side effects.

Many people are choosing to ignore any news about COVID and vaccines but it is still a serious problem, here in the US and around the world. This is a reminder that some people are still getting very sick and dying from the SARS-CoV-2 virus. Updated vaccines are known to reduce the risk of hospitalization and death, so please get one if they are available to you. (Contact your health care provider for any special recommendations that may apply.)

Other measures can also help reduce your chances of getting COVID. Wearing a high quality mask, especially in crowded, indoor areas, dramatically decreases the rate of infection. Increasing indoor ventilation and air filtration and holding events outdoors are helpful in preventing the spread of COVID and other viruses. If you are sick, stay home and take precautions against spreading your illness to others in your household. Get adequate rest and nutrition to keep your immune system strong.

COVID-19 has not settled into a pattern like we see with flu and is still much more serious in terms of hospitalizations and deaths. It also impacts more systems in the body and can cause symptoms over a longer period of time, such as we see in cases of long COVID. Some people are willing to risk their own health but please remember that you are also putting your family and vulnerable community members at risk if you spread the illness to them.

Wishing everyone good health in the coming months.

long COVID research summary

I realize I’ve done A LOT of COVID posts this month, but I had to share this post from Dr. Katelyn Jetelina, writing as “Your Local Epidemiologist.” She gathers together the major research advances in understanding long COVID from 2023, with lots of links to the original research.

One of the main takeaways, which I included in this post earlier in the week, is that vaccines help cut down on long COVID cases, with more doses contributing to lower risks.

Dr. Jetelina also suggests subscribing to The Sick Times newsletter, which is dedicated to sharing the latest information about long COVID weekly.

I’m grateful that the rate of long COVID has declined from early in the pandemic, but it is still affecting millions, some new cases and some months or years old. It’s important to learn more about it so treatments can be developed for long COVID and other post-infection syndromes.
*****
Join us for Linda’s Just Jot It January! You can use provided prompts or post whatever you like, even multiple posts about COVID. (Okay, that’s just me,) Find out more here: https://lindaghill.com/2024/01/19/daily-prompt-jusjojan-the-19th-2024/

Current COVID stats

Update to my COVID post from earlier in the week: Those Nerdy Girls newest post tells us that, using wastewater surveillance, current estimates are that 5% of people in the United States are currently infected with COVID, the largest proportion since the initial Omicron wave two years ago. In the United Kingdom, JN.1 caused a similar wave just before Christmas, with London having an even higher infected rate of almost 6%.

Those Nerdy Girls remind us that about 1,500 people in the United States are dying from COVID every week, making COVID much deadlier than the flu. They also remind us that the COVID vaccine that became available in September ’23 is effective against JN.1 and urge people to receive it if they haven’t already. They also remind people that masking, ventilation, testing, and staying home when you are sick help in avoiding spread not only of COVID but also flu and other viruses.

Please do what you can to keep yourself and others safe and healthy!
*****
Join us for Linda’s Just Jot It January! Find our more here: https://lindaghill.com/2024/01/18/daily-prompt-jusjojan-the-18th-2024/

JN.1

It’s been four years since the first cases of COVID-19 were confirmed in the US but it’s still a major health issue. While vaccines, treatments, and preventative measures have made the current situation less severe than the initial onslaught of SARS-CoV-2, people are still getting sick, with some needing to be hospitalized and some, unfortunately, succumbing to the disease, including the person I referenced in this post. In the week of Dec. 31, 2023-January 6, 2024, COVID caused 4% of all deaths in the United States.

The virus continues to mutate. The current strain that is dominant in the United States and globally is JN.1, which is related to the BA.2.86 variant of Omicron. The good news is that the most recent vaccine, which is based on the related XBB lineage, is a good match for JN.1, so the vaccine significantly reduces the risk of severe symptoms, hospitalization, and death while offering some protection against infection. The bad news is that, in the United States, only about 8% of children and 19% of adults are estimated to have received the newest vaccine, contributing to a surge of cases, amplified by holiday travel and gatherings.

More good vaccine news. This large study from Sweden concludes that vaccination reduces the risk of developing long COVID and that additional vaccine doses reduce risk even more. As someone who has particular concerns about long COVID, I appreciate that these studies are continuing to increase our understanding.

Another recent study shows that the Omicron variants don’t cause peak viral loads until day 3-4, much later than the earlier strains of the virus. The practical implication of this is that at-home COVID tests may not pick up a positive reading until several days into the illness, during which time the person could be infecting others. It also has implications for prescribing anti-virals, which need to begin within the first five days of symptoms to be effective. For me, this is a reminder to mask around other people whenever I have symptoms, as an early negative test might not be accurate.

A study published just a few days ago seems to put some science behind what we have all experienced, that SARS-CoV-2 doesn’t have a “season” in the way that some other viruses, like influenza, do. Changes in temperature and humidity don’t appear to have significant influence in transmission. This seems to go along with what we have experienced in the United States, with major waves happening in different seasons of the year. We’ve had waves in the heat of summer as well as the cold of winter. This suggests that our current winter wave is due more to low vaccination rates and holiday travel and gatherings than to the fact that it is winter. It also highlights the importance of increasing ventilation and using masks in crowded indoor spaces, as both summer heat and winter cold tend to drive people to gather indoors.

Four years in, I’ve written a lot of COVID-19 posts. From my days as part of the Pfizer/BioNTech vaccine trials through the present, I’ve always tried to give the most updated information and public health guidance available. It’s frustrating that there is less information from the Centers for Disease Control and Prevention than when the state of emergency was still in effect but some useful recent data can be found here. A lot of the information in this post came to my attention through this post from Dr. Katelyn Jetelina, writing as “Your Local Epidemiologist” and this post from Those Nerdy Girls.

Through all these challenges, especially when spouse B had the first case of COVID in our house in November, I’ve managed to avoid infection, unless I had a totally asymptomatic case at some point. I use my research to make decisions about vaccination, masking, crowd avoidance, etc. that are right for me and my family. I don’t think that advocating for health measures ought to be seen as controversial or political. There are, though, forces in the US that have warped disease prevention into a political test. It’s very sad that Republicans are more likely to die from COVID than non-Republicans. Please, don’t put your health and the health of your family and neighbors at risk over politics. COVID-19 is still out there. Take care of your health and your loved ones.
*****
Join us for Linda’s Just Jot It January! Find out more here: https://lindaghill.com/2024/01/15/daily-prompt-jusjojan-the-15th-2024/

another COVID-19 risk

I had saved this article on a research study that showed that SARS-CoV-2, the virus that causes COVID-19, can directly infect coronary arteries, which may help to explain the increased risk of heart attack and stroke among people who have contracted it.

It came to mind now because we received news that a friend’s family member with COVID has suffered a heart attack.

While it’s not known if infection and inflammation of the coronary arteries caused this particular person’s heart attack, it is a stark reminder that COVID can cause serious health complications. Way too many people are still getting sick and dying from it.

While there are no iron-clad ways to avoid infection, preventative measures like vaccines, avoiding crowds, and masking in indoor public spaces reduce your chances of infection and its follow-on risks.

Even if you don’t care about your personal risk of infection, remember that you could pass the infection on to someone who may be more vulnerable than you due to their age or underlying health condition. I know this has been a powerful motivating factor for me.

Please do what is right for you to protect yourself and others to the greatest extent possible.
*****
Join us for Linda’s Just Jot It January! Find out more here: https://lindaghill.com/2024/01/08/daily-prompt-jusjojan-the-8th-2024/

out of luck

I’m sad to report that, despite our best efforts, we finally have a case of COVID-19 in the house.

My spouse B tested positive yesterday. We think he was exposed at an in-person work event on Wednesday.

We are taking precautions to isolate from each other but daughter T and I were both exposed to B before he developed symptoms when he was probably infectious, so it’s a waiting game at this point. We’ll be testing before going out in public and masking when we do to avoid infecting anyone else, in case we are pre-symptomatic.

So far, B has had fever and symptoms similar to a bad cold. Our primary care practice wants to hold off on prescribing Paxlovid but will if his condition worsens over the next couple of days.

I knew our luck would run out one day but I’m upset and worried to have COVID in the house. Because I’ve been reading about it and observing the twists and turns in its history since the beginning, I know that things sometimes go very badly, even in someone who is healthy and up-to-date on vaccines, so…

Photo by Martin Sanchez on Unsplash

One-Liner Wednesday: booster

Today, I’m getting my sixth dose of Pfizer/BioNTech COVID-19 vaccine, this one targeting Omicron variant XBB.1.5 and shown to be effective against other currently circulating Omicron sub-variants. Please consider joining me if your health professional or public health agency recommends it for you.
*****
This public health message is brought to you as part of Linda’s One-Liner Wednesdays. Join us! Find out more here: https://lindaghill.com/2023/09/20/one-liner-wednesday-the-ultimate-404-error/

COVID update – late summer 2023

There are many people here in the United States who are no longer taking COVID-19 seriously and a disturbing number who never did.

I am not one of them.

I’ve written dozens of posts over the past three and a half years about it, including about my family’s participation in the Pfizer/BioNTech Phase III clinical trial. I’ve tried to encourage people to take precautions to reduce their chances of infection and serious illness. In that vein, I offer this update.

There was a summer wave in the US with the most prevalent strain being Omicron XBB.1.5. On September 12, the Centers for Disease Control and Prevention Advisory Committee on Immunization Practices will meet to develop a recommendation for a newly formulated booster based on the XBB.1.5 variant. It’s anticipated that the recommendation will be that most people get this new booster, which is expected to be available by the end of September. I will get the booster as soon as I am able. To my knowledge, I’ve still not contracted COVID and would love to keep it that way. Even if the vaccine does not keep me from getting infected, it, along with taking an anti-viral such as Paxlovid, will likely keep me from being hospitalized.

Of course, SARS-CoV-2 continues to mutate. Even now, the variant mix has shifted in the US. EG.5 has become the highest in prevalence with FL.1.5.1 next in an array of variants currently circulating. (You can find current data in the US at the CDC site here.) It is expected that the new booster, though based on XBB.1.5, will still be effective against these other Omicron strains.

The unfortunate wild card at this point is another Omicron variant BA.2.86. The link is to a 8/22 post from epidemiologist Dr. Katelyn Jetelina, explaining why this variant may be more problematic than others, perhaps even warranting the World Health Organization to name it a variant of concern with the name “Pi.” BA.2.86 has over 30 mutations of the spike protein, which is part of the virus that our bodies learn to recognize via vaccines, infection, or both. The fear is that we could see another world-wide wave develop because BA.2.86 might be able to evade our defenses. Researchers are studying it to see if our current tests, vaccines, and treatments will work against it and how it might affect individuals and populations exposed to it. The current number of cases world-wide are thought to be small, but that has been the beginning status of any variant that has become dominant.

Part of the problem is that we don’t have as much data to work with. Most COVID cases aren’t reported to public health authorities anymore. Surveillance and genomic sequencing are lower. This results in less public awareness and information. Theoretically, we should be able to ramp up our system more quickly if a new wave occurs but I wish we had kept up our system in the first place in a proactive stance.

I’m concerned about the attitude that equates COVID infection with other viruses. A study in the journal Nature Medicine shows increased risks for an array of medical conditions, including diabetes, pulmonary and cardiovascular problems, two years after COVID infection, even if the initial case was mild.

“A lot of people think, ‘I got covid, I got over it and I’m fine,’ and it’s a nothingburger for them. But that’s not everything,” said the study’s senior author, Ziyad Al-Aly, a clinical epidemiologist at Washington University School of Medicine in St. Louis. After a couple of years, “maybe you’ve forgotten about the SARS-CoV-2 infection … but covid did not forget about you. It’s still wreaking havoc in your body,” said Al-Aly, chief of research at the Veterans Affairs St. Louis Health Care System.

source: https://www.washingtonpost.com/health/2023/08/21/long-covid-lingering-effects-two-years-later/

The risk of long COVID is real. The article cited above, which is free to access, explains more about the attempts to do research and get care for people with long COVID. People need to realize that they might be someone who gets COVID and has a mild case without long-term repercussions or they might become seriously ill or they might have symptoms for months and years to come. They could also infect someone else who would face the same uncertainties.

I’m once again imploring people to take COVID seriously. Vaccinate, if it is recommended for you. (Being in the US, I’m most familiar with recommendations here but people should look to their own local health authorities and medical practitioners for guidance in their area.) Test and treat an infection. Stay home if you are sick and avoid infecting others. Avoid crowds indoors; wear a high-quality mask if you can’t. If infection rates are significant in your area, mask indoors when you are away from home. Increase ventilation and air filtration. Wash your hands. Get adequate rest and nutrition. Remember that everyone deserves respect, so never question someone else’s decision to mask; they could be immunocompromised, caring for a vulnerable person, etc. and need that protection.

Eventually, we may get to a place where COVID is endemic, like the flu, but we aren’t there yet. Be careful and be kind as we continue to face this still-formidable challenge.